Llwytho...

Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell–cell adhesion

Nectins are members of the Ig superfamily that mediate cell–cell adhesion through homophilic and heterophilic interactions. We have determined the crystal structure of the nectin-2 homodimer at 1.3 Å resolution. Structural analysis and complementary mutagenesis studies reveal the basis for recogniti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Samanta, Dibyendu, Ramagopal, Udupi A., Rubinstein, Rotem, Vigdorovich, Vladimir, Nathenson, Stanley G., Almo, Steven C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443150/
https://ncbi.nlm.nih.gov/pubmed/22927415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212912109
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