Kinin B(1) Receptor in Adipocytes Regulates Glucose Tolerance and Predisposition to Obesity

BACKGROUND: Kinins participate in the pathophysiology of obesity and type 2 diabetes by mechanisms which are not fully understood. Kinin B(1) receptor knockout mice (B(1) (−/−)) are leaner and exhibit improved insulin sensitivity. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that kinin B(1) receptor...

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Main Authors: Mori, Marcelo A., Sales, Vicência Micheline, Motta, Fabiana Louise, Fonseca, Raphael Gomes, Alenina, Natalia, Guadagnini, Dioze, Schadock, Ines, Silva, Elton Dias, Torres, Hugo A. M., dos Santos, Edson Lucas, Castro, Charlles Heldan, D’Almeida, Vânia, Andreotti, Sandra, Campaña, Amanda Baron, Sertié, Rogério A. L., Saad, Mario J. A., Lima, Fabio Bessa, Bader, Michael, Pesquero, João Bosco
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443087/
https://ncbi.nlm.nih.gov/pubmed/23024762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044782
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