Kinin B(1) Receptor in Adipocytes Regulates Glucose Tolerance and Predisposition to Obesity

BACKGROUND: Kinins participate in the pathophysiology of obesity and type 2 diabetes by mechanisms which are not fully understood. Kinin B(1) receptor knockout mice (B(1) (−/−)) are leaner and exhibit improved insulin sensitivity. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that kinin B(1) receptor...

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Hlavní autoři: Mori, Marcelo A., Sales, Vicência Micheline, Motta, Fabiana Louise, Fonseca, Raphael Gomes, Alenina, Natalia, Guadagnini, Dioze, Schadock, Ines, Silva, Elton Dias, Torres, Hugo A. M., dos Santos, Edson Lucas, Castro, Charlles Heldan, D’Almeida, Vânia, Andreotti, Sandra, Campaña, Amanda Baron, Sertié, Rogério A. L., Saad, Mario J. A., Lima, Fabio Bessa, Bader, Michael, Pesquero, João Bosco
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443087/
https://ncbi.nlm.nih.gov/pubmed/23024762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044782
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