Reliability of KRAS mutation testing in metastatic colorectal cancer patients across five laboratories

BACKGROUND: Mutations in the KRAS gene are associated with poor response to epidermal growth factor receptor inhibitors used in the treatment of metastatic colorectal cancer. Factors influencing KRAS test results in tumor specimens include: tumor heterogeneity, sample handling, slide preparation, te...

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Detaylı Bibliyografya
Asıl Yazarlar: Feigelson, Heather Spencer, Goddard, Katrina AB, Johnson, Monique A, Funk, Kellyan C, Rahm, Alanna Kulchak, Kauffman, Tia L, Chitale, Dhananjay A, Le Marchand, Loic, Richards, C Sue
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Short Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441241/
https://ncbi.nlm.nih.gov/pubmed/22534075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-196
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