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Reliability of KRAS mutation testing in metastatic colorectal cancer patients across five laboratories
BACKGROUND: Mutations in the KRAS gene are associated with poor response to epidermal growth factor receptor inhibitors used in the treatment of metastatic colorectal cancer. Factors influencing KRAS test results in tumor specimens include: tumor heterogeneity, sample handling, slide preparation, te...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3441241/ https://ncbi.nlm.nih.gov/pubmed/22534075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-196 |
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