Reliability of KRAS mutation testing in metastatic colorectal cancer patients across five laboratories

BACKGROUND: Mutations in the KRAS gene are associated with poor response to epidermal growth factor receptor inhibitors used in the treatment of metastatic colorectal cancer. Factors influencing KRAS test results in tumor specimens include: tumor heterogeneity, sample handling, slide preparation, te...

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Dades bibliogràfiques
Autors principals: Feigelson, Heather Spencer, Goddard, Katrina AB, Johnson, Monique A, Funk, Kellyan C, Rahm, Alanna Kulchak, Kauffman, Tia L, Chitale, Dhananjay A, Le Marchand, Loic, Richards, C Sue
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441241/
https://ncbi.nlm.nih.gov/pubmed/22534075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-196
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