Reliability of KRAS mutation testing in metastatic colorectal cancer patients across five laboratories

BACKGROUND: Mutations in the KRAS gene are associated with poor response to epidermal growth factor receptor inhibitors used in the treatment of metastatic colorectal cancer. Factors influencing KRAS test results in tumor specimens include: tumor heterogeneity, sample handling, slide preparation, te...

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Bibliografski detalji
Glavni autori: Feigelson, Heather Spencer, Goddard, Katrina AB, Johnson, Monique A, Funk, Kellyan C, Rahm, Alanna Kulchak, Kauffman, Tia L, Chitale, Dhananjay A, Le Marchand, Loic, Richards, C Sue
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Short Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441241/
https://ncbi.nlm.nih.gov/pubmed/22534075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-196
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