Intradermal DNA Vaccination Enhanced by Low-Current Electroporation Improves Antigen Expression and Induces Robust Cellular and Humoral Immune Responses

DNA represents an ideal vaccine platform for HIV and many infectious diseases because of its safety, stability, and ease of manufacture. However, the immunogenicity of DNA vaccines has traditionally been low compared with viral vectors, recombinant protein, and live attenuated vaccines. The immunoge...

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Bibliografische gegevens
Hoofdauteurs: Hutnick, Natalie A., Myles, Devin J.F., Ferraro, Bernadette, Lucke, Colleen, Lin, Feng, Yan, Jian, Broderick, Kate E., Khan, Amir S., Sardesai, Niranjian Y., Weiner, David B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2012
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440022/
https://ncbi.nlm.nih.gov/pubmed/22650607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.055
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