Differentiation and Transplantation of Functional Pancreatic Beta Cells Generated from Induced Pluripotent Stem Cells Derived from a Type 1 Diabetes Mouse Model

The nonobese diabetic (NOD) mouse is a classical animal model for autoimmune type 1 diabetes (T1D), closely mimicking features of human T1D. Thus, the NOD mouse presents an opportunity to test the effectiveness of induced pluripotent stem cells (iPSCs) as a therapeutic modality for T1D. Here, we dem...

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Bibliographic Details
Main Authors: Jeon, Kilsoo, Lim, Hyejin, Kim, Jung-Hyun, Thuan, Nguyen Van, Park, Seung Hwa, Lim, Yu-Mi, Choi, Hye-Yeon, Lee, Eung-Ryoung, Kim, Jin-Hoi, Lee, Myung-Shik, Cho, Ssang-Goo
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2012
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Original Research Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438879/
https://ncbi.nlm.nih.gov/pubmed/22512788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2011.0665
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