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Mispolarization of Desmosomal Proteins and Altered Cell Adhesion in Autosomal Dominant Polycystic Kidney Disease

Polycystin-1, the product of the major gene mutated in autosomal dominant polycystic kidney disease (ADPKD), associates with multiple epithelial cell junctions, including desmosomes. It was our objective to identify the molecular interactions between polycystin-1 and desmosomal components in primary...

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Detalhes bibliográficos
Main Authors: Silberberg, Melina, Charron, Audra J., Bacallao, Robert, Wandinger-Ness, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432402/
https://ncbi.nlm.nih.gov/pubmed/15701820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00008.2005
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