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From Bifunctional to Trifunctional (Tricomponent Nucleophile-Transition Metal-Lewis Acid) Catalysis: The Catalytic, Enantioselective α-Fluorination of Acid Chlorides

We report in full detail our studies on the catalytic, asymmetric α-fluorination of acid chlorides, a practical method that produces an array of α-fluorocarboxylic acid derivatives in which improved yield and virtually complete enantioselectivity are controlled through electrophilic fluorination of...

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Autores principales: Erb, Jeremy, Paull, Daniel H., Dudding, Travis, Belding, Lee, Lectka, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432319/
https://ncbi.nlm.nih.gov/pubmed/21513338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2014345
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