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Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs

Splicing remains an incompletely understood process. Recent findings suggest that chromatin structure participates in its regulation. Here, we analyze the RNA from subcellular fractions obtained through RNA-seq in the cell line K562. We show that in the human genome, splicing occurs predominantly du...

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Main Authors: Tilgner, Hagen, Knowles, David G., Johnson, Rory, Davis, Carrie A., Chakrabortty, Sudipto, Djebali, Sarah, Curado, João, Snyder, Michael, Gingeras, Thomas R., Guigó, Roderic
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2012
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431479/
https://ncbi.nlm.nih.gov/pubmed/22955974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.134445.111
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