Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs

Splicing remains an incompletely understood process. Recent findings suggest that chromatin structure participates in its regulation. Here, we analyze the RNA from subcellular fractions obtained through RNA-seq in the cell line K562. We show that in the human genome, splicing occurs predominantly du...

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Détails bibliographiques
Auteurs principaux: Tilgner, Hagen, Knowles, David G., Johnson, Rory, Davis, Carrie A., Chakrabortty, Sudipto, Djebali, Sarah, Curado, João, Snyder, Michael, Gingeras, Thomas R., Guigó, Roderic
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2012
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431479/
https://ncbi.nlm.nih.gov/pubmed/22955974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.134445.111
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