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Three Routes to Suppression of the Neurodegenerative Phenotypes Caused by Kinesin Heavy Chain Mutations

Kinesin-1 is a motor protein that moves stepwise along microtubules by employing dimerized kinesin heavy chain (Khc) subunits that alternate cycles of microtubule binding, conformational change, and ATP hydrolysis. Mutations in the Drosophila Khc gene are known to cause distal paralysis and lethalit...

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Detaylı Bibliyografya
Asıl Yazarlar: Djagaeva, Inna, Rose, Debra J., Lim, Angeline, Venter, Chris E., Brendza, Katherine M., Moua, Pangkong, Saxton, William M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430534/
https://ncbi.nlm.nih.gov/pubmed/22714410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.140798
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