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Insulin-Loaded pH-Sensitive Hyaluronic Acid Nanoparticles Enhance Transcellular Delivery

In the present study, we developed novel insulin-loaded hyaluronic acid (HA) nanoparticles for insulin delivery. The insulin-loaded HA nanoparticles were prepared by reverse-emulsion-freeze-drying method. This method led to a homogenous population of small HA nanoparticles with average size of 182.2...

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Detalhes bibliográficos
Main Authors: Han, Lina, Zhao, Yuefang, Yin, Lifang, Li, Ruiming, Liang, Yang, Huang, Huan, Pan, Shirong, Wu, Chuanbin, Feng, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429662/
https://ncbi.nlm.nih.gov/pubmed/22644708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9807-2
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