The pH-Sensitive Fusogenic 3-Methyl-Glutarylated Hyperbranched Poly(Glycidol)-Conjugated Liposome Induces Antigen-Specific Cellular and Humoral Immunity

We examined the ability of a novel liposome, surface modified by 3-methyl-glutarylated hyperbranched poly(glycidol) (MGlu-HPG), to enhance antigen-specific immunity in vitro and in vivo and to function as a vaccine carrier. Murine bone marrow-derived dendritic cells took up ovalbumin (OVA) encapsula...

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Autores principales: Hebishima, Takehisa, Yuba, Eiji, Kono, Kenji, Takeshima, Shin-nosuke, Ito, Yoshihiro, Aida, Yoko
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428382/
https://ncbi.nlm.nih.gov/pubmed/22815149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00273-12
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