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Natural killer T cells in adipose tissue prevent insulin resistance

Lipid overload and adipocyte dysfunction are key to the development of insulin resistance and can be induced by a high-fat diet. CD1d-restricted invariant natural killer T (iNKT) cells have been proposed as mediators between lipid overload and insulin resistance, but recent studies found decreased i...

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Detalhes bibliográficos
Main Authors: Schipper, Henk S., Rakhshandehroo, Maryam, van de Graaf, Stan F.J., Venken, Koen, Koppen, Arjen, Stienstra, Rinke, Prop, Serge, Meerding, Jenny, Hamers, Nicole, Besra, Gurdyal, Boon, Louis, Nieuwenhuis, Edward E.S., Elewaut, Dirk, Prakken, Berent, Kersten, Sander, Boes, Marianne, Kalkhoven, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428087/
https://ncbi.nlm.nih.gov/pubmed/22863618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62739
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