Role of Innate Immune Receptors in Paradoxical Caspofungin Activity In Vivo in Preclinical Aspergillosis

This study investigated the possible mechanisms underlying the paradoxical caspofungin activity in vivo in preclinical aspergillosis. We evaluated the activity of escalating doses of caspofungin in vivo in different preclinical models of invasive aspergillosis, including mice deficient for selected...

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Bibliografiska uppgifter
Huvudupphovsmän: Moretti, Silvia, Bozza, Silvia, D'Angelo, Carmen, Casagrande, Andrea, Della Fazia, Maria Agnese, Pitzurra, Lucia, Romani, Luigina, Aversa, Franco
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Experimental Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421572/
https://ncbi.nlm.nih.gov/pubmed/22644025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05198-11
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