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Role of Innate Immune Receptors in Paradoxical Caspofungin Activity In Vivo in Preclinical Aspergillosis

This study investigated the possible mechanisms underlying the paradoxical caspofungin activity in vivo in preclinical aspergillosis. We evaluated the activity of escalating doses of caspofungin in vivo in different preclinical models of invasive aspergillosis, including mice deficient for selected...

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Autors principals: Moretti, Silvia, Bozza, Silvia, D'Angelo, Carmen, Casagrande, Andrea, Della Fazia, Maria Agnese, Pitzurra, Lucia, Romani, Luigina, Aversa, Franco
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421572/
https://ncbi.nlm.nih.gov/pubmed/22644025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05198-11
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