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Unexpected role for perforin in regulating contraction of CD8 and CD4 T cells during prolonged Listeria monocytogenes infection
After infection or vaccination, antigen-specific T cells proliferate then contract in numbers to a memory set point. T cell contraction is observed after both acute and prolonged infections although it is unknown if contraction is regulated similarly in both scenarios. Here, we show that contraction...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418886/ https://ncbi.nlm.nih.gov/pubmed/22161269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141902 |
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