Epithelial Na(+) channel activity in human airway epithelial cells: the role of serum and glucocorticoid-inducible kinase 1

BACKGROUND AND PURPOSE: Glucocorticoids appear to control Na(+) absorption in pulmonary epithelial cells via a mechanism dependent upon serum and glucocorticoid-inducible kinase 1 (SGK1), a kinase that allows control over the surface abundance of epithelial Na(+) channel subunits (α-, β- and γ-ENaC)...

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Bibliographic Details
Main Authors: Watt, Gordon B, Ismail, Noor AS, Caballero, Agustin Garcia, Land, Stephen C, Wilson, Stuart M
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2012
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417446/
https://ncbi.nlm.nih.gov/pubmed/22250980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01860.x
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