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Identification and Characterization of ZEL-H16 as a Novel Agonist of the Histamine H(3) Receptor

The histamine H3 receptor (H3R) has been recognized as a promising target for the treatment of various central and peripheral nervous system diseases. In this study, a non-imidazole compound, ZEL-H16, was identified as a novel histamine H3 receptor agonist. ZEL-H16 was found to bind to human H3R wit...

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Bibliografski detalji
Glavni autori: Shi, Ying, Sheng, Rong, Zhong, Tingting, Xu, Yu, Chen, Xiaopan, Yang, Dong, Sun, Yi, Yang, Fenyan, Hu, Yongzhou, Zhou, Naiming
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411647/
https://ncbi.nlm.nih.gov/pubmed/22870296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042185
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