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Racemization of Two Proteins over Our Lifespan: Deamidation of Asparagine 76 in γS Crystallin Is Greater in Cataract than in Normal Lenses across the Age Range
PURPOSE. Long-lived proteins are widespread in man, yet little is known about the processes that affect their function over time, or their role in age-related diseases. METHODS. Racemization of two proteins from normal and cataract human lenses were compared with age using tryptic digestion and LC/m...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Association for Research in Vision and Ophthalmology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406884/ https://ncbi.nlm.nih.gov/pubmed/22531704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-9085 |
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