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A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity

Recombinant adenoviruses are among the most promising tools for vaccine antigen delivery. Recently, the development of new vectors has focused on serotypes to which the human population is less exposed in order to circumvent pre-existing anti vector immunity. This study describes the derivation of a...

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Autors principals: Dicks, Matthew D. J., Spencer, Alexandra J., Edwards, Nick J., Wadell, Göran, Bojang, Kalifa, Gilbert, Sarah C., Hill, Adrian V. S., Cottingham, Matthew G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396660/
https://ncbi.nlm.nih.gov/pubmed/22808149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040385
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