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Abnormal Histone Methylation is Responsible for Increased VEGF165a Secretion from Airway Smooth Muscle Cells in Asthma

Vascular Endothelial Growth Factor (VEGF), a key angiogenic molecule, is aberrantly expressed in several diseases including asthma where it contributes to bronchial vascular remodelling and chronic inflammation. Asthmatic human airway smooth muscle (HASM) cells hypersecrete VEGF but the mechanism is...

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Detalhes bibliográficos
Main Authors: Clifford, Rachel L., John, Alison E., Brightling, Christopher E., Knox, Alan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393638/
https://ncbi.nlm.nih.gov/pubmed/22689881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103641
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