Graded levels of Pax2a and Pax8 regulate cell differentiation during sensory placode formation

Pax gene haploinsufficiency causes a variety of congenital defects. Renal-coloboma syndrome, resulting from mutations in Pax2, is characterized by kidney hypoplasia, optic nerve malformation, and hearing loss. Although this underscores the importance of Pax gene dosage in normal development, how dif...

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Detaylı Bibliyografya
Asıl Yazarlar: McCarroll, Matthew N., Lewis, Zachary R., Culbertson, Maya Deza, Martin, Benjamin L., Kimelman, David, Nechiporuk, Alex V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2012
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392703/
https://ncbi.nlm.nih.gov/pubmed/22745314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.076075
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