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The Integrin-Ligand Interaction Regulates Adhesion and Migration through a Molecular Clutch

Adhesive and migratory behavior can be cell type, integrin, and substrate dependent. We have compared integrin and substrate differences using three integrin receptors: α5β1, α6β1, and αLβ2 expressed in a common cell type, CHO.B2 cells, which lack integrin α subunits, as well as in different cell ty...

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Autores principales: Chen, Lingfeng, Vicente-Manzanares, Miguel, Potvin-Trottier, Laurent, Wiseman, Paul W., Horwitz, Alan Rick
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391238/
https://ncbi.nlm.nih.gov/pubmed/22792239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040202
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