Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses

SIRT6 is involved in inflammation, aging and metabolism potentially by modulating the functions of both NFκB and HIF1α. Since it is possible to make small molecule activators and inhibitors of Sirtuins we wished to establish biochemical and cellular assays both to assist in drug discovery efforts an...

詳細記述

保存先:
書誌詳細
主要な著者: Grimley, Rachel, Polyakova, Oxana, Vamathevan, Jessica, McKenary, Joanne, Hayes, Brian, Patel, Champa, Smith, Janet, Bridges, Angela, Fosberry, Andrew, Bhardwaja, Anshu, Mouzon, Bernadette, Chung, Chun-Wa, Barrett, Nathalie, Richmond, Nicola, Modha, Sundip, Solari, Roberto
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391194/
https://ncbi.nlm.nih.gov/pubmed/22792191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039847
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料