Reduction of Burn Progression with Topical Delivery of (Anti-Tumor Necrosis Factor-α)-Hyaluronic Acid Conjugates

In this study, we explored whether topical application of antibodies targeting tumor necrosis factor-α (TNF-α) or interleukin-6 (IL-6) conjugated to hyaluronic acid (HA) could reduce the extension of necrosis by modulating inflammation locally in a partial-thickness rat burn model. Partial-thickness...

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Main Authors: Sun, Liang Tso, Friedrich, Emily, Heuslein, Joshua L., Pferdehirt, Rachel E., Dangelo, Nicole M., Natesan, Shanmugasundaram, Christy, Robert J., Washburn, Newell R.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389270/
https://ncbi.nlm.nih.gov/pubmed/22712482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1524-475X.2012.00813.x
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