Control of T(H)17/T(reg) Balance by Hypoxia-inducible Factor 1

T cell differentiation into distinct functional effector and inhibitory subsets is regulated in part by the cytokine environment present at the time of antigen recognition. Here, we show that hypoxia-inducible factor 1 (HIF-1), a key metabolic sensor, regulates the balance between T regulatory (T(re...

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Main Authors: Dang, Eric V., Barbi, Joseph, Yang, Huang-Yu, Jinasena, Dilini, Yu, Hong, Zheng, Ying, Bordman, Zachary, Fu, Juan, Kim, Young, Yen, Hung-Rong, Luo, Weibo, Zeller, Karen, Shimoda, Larissa, Topalian, Suzanne L., Semenza, Gregg L., Dang, Chi V., Pardoll, Drew M., Pan, Fan
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387678/
https://ncbi.nlm.nih.gov/pubmed/21871655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.033
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