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Role of Serotonin Neurons in L-DOPA- and Graft-Induced Dyskinesia in a Rat Model of Parkinson's Disease

L-DOPA, the most effective drug to treat motor symptoms of Parkinson's disease, causes abnormal involuntary movements, limiting its use in advanced stages of the disease. An increasing body of evidence points to the serotonin system as a key player in the appearance of L-DOPA-induced dyskinesia...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shin, Eunju, Tronci, Elisabetta, Carta, Manolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384974/
https://ncbi.nlm.nih.gov/pubmed/22762012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/370190
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