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Ablation of sarcolipin results in atrial remodeling
Sarcolipin (SLN) is a key regulator of sarco(endo)plasmic reticulum (SR) Ca(2+)-ATPase (SERCA), and its expression is altered in diseased atrial myocardium. To determine the precise role of SLN in atrial Ca(2+) homeostasis, we developed a SLN knockout (sln−/−) mouse model and demonstrated that ablat...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378074/ https://ncbi.nlm.nih.gov/pubmed/22496245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00425.2011 |
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