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A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell death
Exposure of insulin-producing cells to elevated levels of the free fatty acid (FFA) palmitate results in the loss of β-cell function and induction of apoptosis. The induction of endoplasmic reticulum (ER) stress is one mechanism proposed to be responsible for the loss of β-cell viability in response...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378068/ https://ncbi.nlm.nih.gov/pubmed/22436701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00519.2011 |
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