The Extracellular Matrix Molecule Hyaluronic Acid Regulates Hippocampal Synaptic Plasticity by Modulating Postsynaptic L-Type Ca(2+) Channels

Although the extracellular matrix plays an important role in regulating use-dependent synaptic plasticity, the underlying molecular mechanisms are poorly understood. Here we examined the synaptic function of hyaluronic acid (HA), a major component of the extracellular matrix. Enzymatic removal of HA...

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Autors principals: Kochlamazashvili, Gaga, Henneberger, Christian, Bukalo, Olena, Dvoretskova, Elena, Senkov, Oleg, Lievens, Patricia M.-J., Westenbroek, Ruth, Engel, Andreas K., Catterall, William A., Rusakov, Dmitri A., Schachner, Melitta, Dityatev, Alexander
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378029/
https://ncbi.nlm.nih.gov/pubmed/20624596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.05.030
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