SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing

The stratum corneum (SC), the outermost layer of the epidermis, acts as a barrier against the external environment. It is hydrated by endogenous humectants to avoid desiccation. However, the molecular mechanisms of SC hydration remain unclear. We report that skin-specific retroviral-like aspartic pr...

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Hlavní autoři: Matsui, Takeshi, Miyamoto, Kenichi, Kubo, Akiharu, Kawasaki, Hiroshi, Ebihara, Tamotsu, Hata, Kazuya, Tanahashi, Shinya, Ichinose, Shizuko, Imoto, Issei, Inazawa, Johji, Kudoh, Jun, Amagai, Masayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: WILEY-VCH Verlag 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377080/
https://ncbi.nlm.nih.gov/pubmed/21542132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100140
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