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Apples to origins: Identifying brain tumor stem cell genes by comparing transcriptomes of normal and cancer stem cells

The mechanisms whereby medulloblastoma stem cells coordinate tumor propagation are poorly understood. Utilizing microarray analysis, Corno and colleagues draw parallels and distinctions between medulloblastoma stem cells from the Ptch(+/−) mouse and normal neural stem cells, identifying Ebf3 as a ca...

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Autori principali: Wortham, Matthew, Yan, Hai
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375910/
https://ncbi.nlm.nih.gov/pubmed/22684456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0182
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