Anti-AIDS agents 88. Anti-HIV conjugates of betulin and betulinic acid with AZT prepared via click chemistry

In the present study, a new strategy to link AZT with betulin/betulinic acid (BA) by click chemistry was designed and achieved. This conjugation via a triazole linkage offers a new direction for modification of anti-HIV triterpenes. Click chemistry provides an easy and productive way for linking two...

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Bibliographic Details
Main Authors: Bori, Ibrahim D., Hung, Hsin-Yi, Qian, Keduo, Chen, Chin-Ho, Morris-Natschke, Susan L., Lee, Kuo-Hsiung
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375835/
https://ncbi.nlm.nih.gov/pubmed/22711941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.02.022
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