Probenecid: novel use as a non-injurious positive inotrope acting via cardiac TRPV2 stimulation

Probenecid is a highly lipid soluble benzoic acid derivative originally used to increase serum antibiotic concentrations. It was later discovered to have uricosuric effects and was FDA approved for gout therapy. It has recently been found to be a potent agonist of Transient Receptor Potential Vanill...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Koch, Sheryl E., Gao, Xiaoqian, Haar, Lauren, Jiang, Min, Lasko, Valerie M., Robbins, Nathan, Cai, Wenfeng, Brokamp, Cole, Varma, Priyanka, Tranter, Michael, Liu, Yong, Ren, Xiaoping, Lorenz, John N., Wang, Hong-Sheng, Jones, W. Keith, Rubinstein, Jack
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372642/
https://ncbi.nlm.nih.gov/pubmed/22561103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.04.011
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