Mechanical Disassembly of Single Virus Particles Reveals Kinetic Intermediates Predicted by Theory

New experimental approaches are required to detect the elusive transient intermediates predicted by simulations of virus assembly or disassembly. Here, an atomic force microscope (AFM) was used to mechanically induce partial disassembly of single icosahedral T = 1 capsids and virions of the minute v...

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Detalles Bibliográficos
Main Authors: Castellanos, Milagros, Pérez, Rebeca, Carrillo, Pablo J.P., de Pablo, Pedro J., Mateu, Mauricio G.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2012
Assuntos:
Proteins
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368135/
https://ncbi.nlm.nih.gov/pubmed/22713577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.026
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