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Structural Adaptation of a Thermostable Biotin-binding Protein in a Psychrophilic Environment
Shwanavidin is an avidin-like protein from the marine proteobactrium Shewanella denitrificans, which exhibits an innate dimeric structure while maintaining high affinity toward biotin. A unique residue (Phe-43) from the L3,4 loop and a distinctive disulfide bridge were shown to account for the high...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365750/ https://ncbi.nlm.nih.gov/pubmed/22493427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.357186 |
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