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Heterotrimer-independent regulation of activation-loop phosphorylation of Snf1 protein kinase involves two protein phosphatases

The SNF1/AMP-activated protein kinases are αβγ-heterotrimers that sense and regulate energy status in eukaryotes. They are activated by phosphorylation of the catalytic Snf1/α subunit, and the Snf4/γ regulatory subunit regulates phosphorylation through adenine nucleotide binding. In Saccharomyces ce...

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Autors principals: Ruiz, Amparo, Liu, Yang, Xu, Xinjing, Carlson, Marian
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365208/
https://ncbi.nlm.nih.gov/pubmed/22589305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206280109
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