Nicorandil as a novel therapy for advanced diabetic nephropathy in the eNOS-deficient mouse

Nicorandil is an orally available drug that can act as a nitric oxide donor, an antioxidant, and an ATP-dependent K channel activator. We hypothesized that it may have a beneficial role in treating diabetic nephropathy. We administered nicorandil to a model of advanced diabetic nephropathy (the stre...

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Hauptverfasser: Tanabe, Katsuyuki, Lanaspa, Miguel A., Kitagawa, Wataru, Rivard, Christopher J., Miyazaki, Makoto, Klawitter, Jelena, Schreiner, George F., Saleem, Moin A., Mathieson, Peter W., Makino, Hirofumi, Johnson, Richard J., Nakagawa, Takahiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362173/
https://ncbi.nlm.nih.gov/pubmed/22338086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00596.2011
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