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AMPK Activation by Dihydrotestosterone Reduces FSH-Stimulated Cell Proliferation in Rat Granulosa Cells by Inhibiting ERK Signaling Pathway

We have previously reported that 5α-dihydrotestosterone (DHT) inhibits FSH-mediated granulosa cell proliferation by reducing cyclin D2 mRNA expression and blocking cell cycle progression at G1/S phase. The present study investigated the role of AMP activated protein kinase (AMPK) in DHT-mediated inh...

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Detalles Bibliográficos
Main Authors: Kayampilly, Pradeep P., Menon, K. M. J.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359611/
https://ncbi.nlm.nih.gov/pubmed/22454147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1967
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