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Neural Crest Cell Survival Is Dependent on Rho Kinase and Is Required for Development of the Mid Face in Mouse Embryos

Neural crest cells (NCC) give rise to much of the tissue that forms the vertebrate head and face, including cartilage and bone, cranial ganglia and teeth. In this study we show that conditional expression of a dominant-negative (DN) form of Rho kinase (Rock) in mouse NCC results in severe hypoplasia...

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書誌詳細
主要な著者: Phillips, Helen M., Papoutsi, Tania, Soenen, Helena, Ybot-Gonzalez, Patricia, Henderson, Deborah J., Chaudhry, Bill
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357402/
https://ncbi.nlm.nih.gov/pubmed/22629443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037685
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