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Neural Crest Cell Survival Is Dependent on Rho Kinase and Is Required for Development of the Mid Face in Mouse Embryos

Neural crest cells (NCC) give rise to much of the tissue that forms the vertebrate head and face, including cartilage and bone, cranial ganglia and teeth. In this study we show that conditional expression of a dominant-negative (DN) form of Rho kinase (Rock) in mouse NCC results in severe hypoplasia...

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Autors principals: Phillips, Helen M., Papoutsi, Tania, Soenen, Helena, Ybot-Gonzalez, Patricia, Henderson, Deborah J., Chaudhry, Bill
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357402/
https://ncbi.nlm.nih.gov/pubmed/22629443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037685
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