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Toxin Pores Endocytosed During Plasma Membrane Repair Traffic into the Lumen of MVBs for Degradation

Cells permeabilized by the bacterial pore-forming toxin streptolysin O (SLO) reseal their plasma membrane in a Ca(2+)-dependent manner. Resealing involves Ca(2+)-dependent exocytosis of lysosomes, release of acid sphingomyelinase and rapid formation of endosomes that carry the transmembrane pores in...

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Bibliographic Details
Main Authors: Corrotte, Matthias, Fernandes, Maria Cecilia, Tam, Christina, Andrews, Norma W.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356596/
https://ncbi.nlm.nih.gov/pubmed/22212686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2011.01323.x
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