Inhibition of High-Mobility Group Box 1 Protein (HMGB1) Enhances Bacterial Clearance and Protects against Pseudomonas Aeruginosa Pneumonia in Cystic Fibrosis

Pulmonary infection with Pseudomonas aeruginosa and neutrophilic lung inflammation significantly contribute to morbidity and mortality in cystic fibrosis (CF). High-mobility group box 1 protein (HMGB1), a ubiquitous DNA binding protein that promotes inflammatory tissue injury, is significantly eleva...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Entezari, Maria, Weiss, Daniel J, Sitapara, Ravikumar, Whittaker, Laurie, Wargo, Matthew J, Li, JianHua, Wang, Haichao, Yang, Huan, Sharma, Lokesh, Phan, Binh D, Javdan, Mohammad, Chavan, Sangeeta S, Miller, Edmund J, Tracey, Kevin J, Mantell, Lin L
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: ScholarOne 2012
Θέματα:
Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356431/
https://ncbi.nlm.nih.gov/pubmed/22314397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00024
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