Exposure to Lipopolysaccharide and/or Unconjugated Bilirubin Impair the Integrity and Function of Brain Microvascular Endothelial Cells

BACKGROUND: Sepsis and jaundice are common conditions in newborns that can lead to brain damage. Though lipopolysaccharide (LPS) is known to alter the integrity of the blood-brain barrier (BBB), little is known on the effects of unconjugated bilirubin (UCB) and even less on the joint effects of UCB...

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Main Authors: Cardoso, Filipa L., Kittel, Ágnes, Veszelka, Szilvia, Palmela, Inês, Tóth, Andrea, Brites, Dora, Deli, Mária A., Brito, Maria A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346740/
https://ncbi.nlm.nih.gov/pubmed/22586454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035919
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