PF-04494700, an Oral Inhibitor of Receptor For Advanced Glycation End Products (RAGE), in Alzheimer’s disease

OBJECTIVE: To evaluate the safety and tolerability of PF-04494700, an oral Inhibitor of receptor for advanced glycation end products (RAGE), in subjects with mild-to-moderate dementia of the Alzheimer’s type. METHODS: Subjects 50 years and older who met NINCDS-ADRDA criteria for AD with an MMSE scor...

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Autori principali: Sabbagh, Marwan N., Agro, Albert, Bell, Joanne, Aisen, Paul S., Schweizer, Edward, Galasko, Douglas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346183/
https://ncbi.nlm.nih.gov/pubmed/21192237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WAD.0b013e318204b550
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