Curcumin inhibits interferon-γ signaling in colonic epithelial cells

Curcumin (diferulolylmethane) is an anti-inflammatory phenolic compound found effective in preclinical models of inflammatory bowel diseases (IBD) and in ulcerative colitis patients. Pharmacokinetics of curcumin and its poor systemic bioavailability suggest that it targets preferentially intestinal...

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Main Authors: Midura-Kiela, Monica T., Radhakrishnan, Vijayababu M., Larmonier, Claire B., Laubitz, Daniel, Ghishan, Fayez K., Kiela, Pawel R.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2012
Assuntos:
Hormones and Signaling
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345961/
https://ncbi.nlm.nih.gov/pubmed/22038826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00275.2011
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